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More recently Funk, and Bradd and Cooper, found that when fowls were allowed a fixed amount vitamine, the greater the proportion carbohydrate in the food, best rated essay writing service the quicker was the onset polyneuritis.

From thn evidence these investigatoTBcoBcMe that the vitamines play an active pay for writing rdle in the assimilation and metabolism carbohydrates, and that in this way rather than as a building stone for nervous tissues tiiat vitamines are essential the Hfe the organism.

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It appears that this ccmclueion premature say tiie least. It has always been supposed that carlx ydrate foods were chiefly value in the animal economy a fnd, or as a source heat and energy, ratiier than as tissue builders. It seems highly obable that carbohydrates are such importance in tiie metabdism tiie nervous tissue, that a hult in cnbc ydrate metabolinn would result in tiie profound degeneration the nervous system seen in beriberi. But aside from such a priori how to find someone to write my paper reasoning, there experimental evidence which difficult reconcile with such a theory.

Schanmaon, produced paralysis with evidence degeneration in the nerves, in both rats and dogs feeding them exclusively meat that had been sterilised in an autoclave at. If beriberi and nerve degenen ons may produced as the result the destruction the vitamines in animals that eat no carbohydrate food, this would appear show that the vitamines are essential the body in some other way than as factor in carbohydrate metabolism.

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Funk performed one experiment in an endeavor show that beriberi not an intoxication, difficult reconcile with the theory that the vitamine concerned in carbohydrate metabolism. Four healthy doves and four doves in the last stages polyneuritis were killed, plucked, and finely minced and extracted with three times their volume absolute alcohol in a shaking machine. The extracts were filtered and evaporated in vacuo. The residues were taken with water and fed mouth birds suffering from polyneuritis.

In all eight cases a cure was effected, with the extract from birds suffering.from polyneuritis, as well as with the extract from normal birds. This contradicts the intoxication theory, since no trace intoxication resulted from the administration extracts birds suffering from polyneuritis, but the contrary a cure. The extract from healthy birds contained more vitamine. need help writing a thesis Funk says This exi eriment shows that all the vitamines an organism can not mobilized take part in metabolism. It appears also that the organs most essential life are the ones first robbed and the animal dies before the whole supply vitamine exhausted from the body.

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It appears that Funk here admits what elsewhere denies, namely, that the vitamines exist in the body as constituents the tissues and particularly nervous essay editing services tissue.

Further experiments are greatly needed determine the exact e the vitamines in the metabolism the body. But at present I see no reason doubt that one them concerned in some way with the metabolism nervous tissue, probably as a building stone, and that this the most plausible explanation the degeneration the nervous system in beriberi, which occurs when this vitamine withdrawn. WTuU the ehemUtry vitaminetf The study the chemistry the vitamines has been a source confusion. Funk claimed have obtained the viatmine from rice polishings in a pure state and gave its empirical formula. Edie and his coworkers obtained a different formula. Suzuki and Shimamura and Odake a different method obtained a vitamine still different chemical composition. Two facts were considered primary importance in determining the direction the work. 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